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Siglec H antibody (FITC)

Reactivity: Mouse FACS Host: Rat Monoclonal 551 FITC
Catalog No. ABIN2661989
  • Target See all Siglec H products
    Siglec H
    Reactivity
    Mouse
    Host
    • 8
    Rat
    Clonality
    • 8
    Monoclonal
    Conjugate
    • 4
    • 3
    • 1
    This Siglec H antibody is conjugated to FITC
    Application
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Characteristics
    The Siglec-H is a member of CD33-related Siglec family which mostly expressed in the innate immune system. Siglec-H is reported to be specifically expressed on plasmacytoid dendritic cells. Siglec-H depends on adaptor protein DAP 12 (DNAX-activating protein of 12 kD) for surface expression and signal transduction. Cross-linking with this antibody can selectively inhibit interferon-alpha production by IPCs following TLR9 ligation.
    Purification
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Clone
    551
    Isotype
    IgG1, IgG1 kappa
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    Siglec H
    Abstract
    Siglec H Products
    Synonyms
    6430529G09Rik antibody, Siglec-H antibody, sialic acid binding Ig-like lectin H antibody, Siglech antibody
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