ITGA6 antibody (Pacific Blue)

Catalog No. ABIN2662280

The Pacific Blue-conjugated Rat Monoclonal anti-ITGA6 antibody (Clone GoH3) (ABIN2662280) specifically detects ITGA6 in FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for ITGA6 antibody (Pacific Blue) (ABIN2662280)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA6 antibody is conjugated to Pacific Blue

Application: Flow Cytometry (FACS)

Clone: GoH3

Product Details anti-ITGA6 Antibody (Pacific Blue)

Cross-Reactivity: Baboon, Cynomolgus, Rhesus Monkey, Horse (Equine), Cow (Bovine), Sheep (Ovine), Pig (Porcine), Dog (Canine), Cat (Feline), Rabbit, Capuchin Monkey, Chicken, Chimpanzee

Purification: The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: CD49f

Background: CD49f is a 120 kD integrin family member also known as VLA-6 α chain and α6 integrin subunit. CD49f associates with either integrin β1 (CD29) or integrin β4 (CD104) to form receptors (VLA-6 or α6β4 complex) for laminin and kalinin. CD49f is expressed on platelets, monocytes, T cells, placental trophoblasts, and epithelial and endothelial cells. CD49f is involved in adhesion and can act as a co-stimulatory molecule for T cell activation and proliferation.

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex