CRTAM antibody (PE)

Catalog No. ABIN2662609

The Rat Monoclonal anti-CRTAM antibody is suitable to detect CRTAM in samples from Mouse. It has been validated for FACS and IP.

Quick Overview for CRTAM antibody (PE) (ABIN2662609)

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CRTAM antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: 11-5-CRTAM

Product Details anti-CRTAM Antibody (PE)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CRTAM

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Alternative Name: CD355

Background: Class-I MHC-restricted T-cell associated molecule (CRTAM), designated as CD355, is an Ig domain like type I transmembrane receptor, which belongs to the nectin family. In the immune system, CRTAM is strictly expressed on activated NK cells and activated CD8-positive T cells. By binding its ligand Nectin-like molecule 2 (Necl2), CRTAM plays an important role in mediating cell adhesion and migration.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation