CD4 antibody (PE)

Catalog No. ABIN2662640

This anti-CD4 antibody is a Rat Monoclonal antibody detecting CD4 in FACS, WB, IHC, IP, IF, BR, Dep, Act and CMCD. Suitable for Human.

Quick Overview for CD4 antibody (PE) (ABIN2662640)

Target: CD4

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to PE

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Blocking Reagent (BR), Depletion (Dep), Activation (Act), Complement Mediated Cell Depletion (CMCD)

Clone: A161A1

Product Details anti-CD4 Antibody (PE)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events