ITGA2 antibody (PE)

Catalog No. ABIN2662654

The Mouse Monoclonal anti-ITGA2 antibody has been validated for FACS. It is suitable to detect ITGA2 in samples from Human.

Quick Overview for ITGA2 antibody (PE) (ABIN2662654)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: P1E6-C5

Product Details anti-ITGA2 Antibody (PE)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: CD49b

Background: CD49b is a 170 kD transmembrane protein, also known as α2 integrin, VLA-2 α chain, Integrin α2 and GPIa. It associates with CD29 (β1 integrin) to form VLA-2, a collagen and laminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts. CD49b has been reported to interact with F-actin and matrix metalloproteinase 1. CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocytopenia. Deficiencies in this protein have been associated with hemorrhagic disorders.

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex