CX3CR1 antibody (PE)

Catalog No. ABIN2662696

The Mouse Monoclonal anti-CX3CR1 antibody is suitable to detect CX3CR1 in samples from Human. It has been validated for FACS.

Quick Overview for CX3CR1 antibody (PE) (ABIN2662696)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CX3CR1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: K0124E1

Product Details anti-CX3CR1 Antibody (PE)

Cross-Reactivity: Cynomolgus, Rhesus Monkey

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1

Background: CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also known as GPR13 or V28. It is expressed on NK cells, T cell subset, monocytes/macrophages, dendritic cells, and some malignant epithelial cells. CX3CL1 (known as fractalkine, neurotactin) is the ligand of CX3CR1. CX3CL1 is a unique transmembrane molecule with a CX3C-motif chemokine domain and a mucin-like stalk. CX3CL1 is expressed by activated-endothelial cells, neurons, and astrocytes. The interaction of CX3CR1 and its ligand mediates cell firm adhesion and migration.

Pathways: Cellular Response to Molecule of Bacterial Origin