SIRPG antibody (PE)

Catalog No. ABIN2663096

Product Details anti-SIRPG Antibody (PE)

Target: SIRPG (Signal-Regulatory Protein gamma (SIRPG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIRPG antibody is conjugated to PE

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: LSB2-20

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for SIRPG

Target: SIRPG (Signal-Regulatory Protein gamma (SIRPG))

Alternative Name: CD172g (SIRPG Products)

Synonyms: CD172g antibody, SIRP-B2 antibody, SIRPB2 antibody, SIRPgamma antibody, bA77C3.1 antibody, SIRPG antibody, signal regulatory protein gamma antibody, signal-regulatory protein gamma antibody, SIRPG antibody, LOC716034 antibody, LOC102138723 antibody

Background: Signal Regulatory Proteins (SIRPs) comprise a family of several transmembrane glycoproteins (SIRPα, SIRPβ, and SIRPγ) that belong to immunoglobulin superfamily. SIRPγ is also known as CD172g or SIRPβ2 which is primarily expressed on T cells and a subpopulation of B cells. Like CD172a, the ligand of CD172g is CD47. But the binding affinity with CD172g is lower than CD172a. The biological functions of CD172g include regulation of T-cell transendothelial migration and induction of T cell apoptosis.