VPREB1 antibody (PE)

Catalog No. ABIN2663102

The PE-conjugated Mouse Monoclonal anti-VPREB1 antibody (Clone HSL96) (ABIN2663102) specifically detects VPREB1 in WB, IHC, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for VPREB1 antibody (PE) (ABIN2663102)

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VPREB1 antibody is conjugated to PE

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: HSL96

Product Details anti-VPREB1 Antibody (PE)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for VPREB1

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Alternative Name: CD179a

Background: CD179a is an 18 kD Ig V-like protein expressed on pro-B and early pre-B cells. It is a member of the Ig gene superfamily, known as VpreB, VPREB1, and IGVPB. CD179a noncovalently associates with CD179b (λ5) to form a surrogate light (SL) chain. The SL chain is complexed with membrane bound IgM heavy (μH) chain and CD79a/CD79b heterodimer to form the pre-B-cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation though it has been reported that the pre-BCR complex plays a critical role in B cell development.

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size