VPREB1 antibody

Catalog No. ABIN7232112

The Rabbit Polyclonal anti-VPREB1 antibody is suitable to detect VPREB1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for VPREB1 antibody (ABIN7232112)

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPREB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VPREB1 Antibody

Purpose: Rabbit Anti-VPREB Polyclonal Antibody

Specificity: The antibody detects endogenous levels of VPREB protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human VPREB protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for VPREB1

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Alternative Name: VPREB

Background: Immunoglobulin iota chain, CD179 antigen-like family member A, Protein VPreB1, V(pre)B protein, VpreB protein, CD179aThe protein encoded by VPREB1 belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. VPREB1 encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants.

Molecular Weight: 15kD

Gene ID: 7441

UniProt: P12018

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size