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CD59 antibody (PE)

This Mouse Monoclonal antibody specifically detects CD59 in FACS. It exhibits reactivity toward Human.
Catalog No. ABIN2663538

Quick Overview for CD59 antibody (PE) (ABIN2663538)

Target

See all CD59 Antibodies
CD59

Reactivity

  • 168
  • 15
  • 11
  • 8
  • 5
  • 4
  • 3
  • 1
  • 1
Human

Host

  • 99
  • 92
  • 7
  • 6
Mouse

Clonality

  • 121
  • 80
  • 1
Monoclonal

Conjugate

  • 85
  • 26
  • 15
  • 14
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD59 antibody is conjugated to PE

Application

  • 115
  • 90
  • 67
  • 54
  • 47
  • 39
  • 28
  • 23
  • 16
  • 14
  • 13
  • 13
  • 11
  • 11
  • 9
  • 8
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

P282 (H19)
  • Cross-Reactivity

    Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey

    Purification

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    Isotype

    IgG2a kappa
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Protect from prolonged exposure to light. Do not freeze.

    Storage

    4 °C

    Storage Comment

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    CD59

    Alternative Name

    CD59

    Background

    CD59 is a 19-25 kD glycosylphosphatidylinositol (GPI)-anchored glycoprotein also known as protectin, MACIF, and H19. It is broadly expressed on hematopoietic and non-hematopoietic cells. CD59 inhibits the cytolytic activity of complement by binding to C9, inhibiting incorporation into C5b-8, and preventing the terminal steps in complement polymerization of the membrane attack complex. CD59 has also been reported to play a role in T cell activation.

    Pathways

    Complement System
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