LY86 antibody (PE)

Catalog No. ABIN2663846

The PE-conjugated Rat Monoclonal anti-LY86 antibody (Clone MD-113) (ABIN2663846) specifically detects LY86 in FACS. The antibody is reactive with Mouse samples.

Quick Overview for LY86 antibody (PE) (ABIN2663846)

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This LY86 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: MD-113

Product Details anti-LY86 Antibody (PE)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for LY86

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Alternative Name: MD-1

Background: MD-1 is a small 28-kD molecule that is usually found in association with CD180 (RP105), a member of the Toll-like receptor family. MD-1 is primarily expressed by B cells, dendritic cells and monocytes, and promotes the recognition of, and subsequent signaling by, LPS in the innate immune system. The MD-113 antibody is reported to be antagonistic for LPS-induced B cell proliferation.

Pathways: Toll-Like Receptors Cascades