CD300LG antibody

Catalog No. ABIN2664534

This Rat Monoclonal antibody specifically detects CD300LG in IF. It exhibits reactivity toward Mouse.

Quick Overview for CD300LG antibody (ABIN2664534)

Target: CD300LG (TREM4) (Triggering Receptor Expressed On Myeloid Cells 4 (TREM4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD300LG antibody is un-conjugated

Application: Immunofluorescence (IF)

Clone: ZAQ5

Product Details anti-CD300LG Antibody

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD300LG

Target: CD300LG (TREM4) (Triggering Receptor Expressed On Myeloid Cells 4 (TREM4))

Alternative Name: CD300LG

Background: CD300LG, also known as nepmucin (a not expressed in Peyer's patches mucin), is a member of the CD300 antigen like family. It is a 50-95 kD glycoprotein with one IgV like domain and one mucin like domain and four isoforms are produced by alternative splicing. Nepmucin is expressed on high endothelial venules (HEV) from lymph nodes, but is absent on HEV from the Peyer's patches. CD300LG mediates lymphocyte adhesion through the intraction of its Ig domain with ICAM-1 and rolling on HEVs through the interaction of its mucin like domain with L-selectine. Also, it may play a role in the molecular transcytosis across the capillary endothelium.