DLL4 antibody

Catalog No. ABIN2664931

The Mouse Monoclonal anti-DLL4 antibody has been validated for MA. It is suitable to detect DLL4 in samples from Human.

Quick Overview for DLL4 antibody (ABIN2664931)

Target: DLL4 (delta-Like 4 (DLL4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: Multiplex Assay (MA)

Clone: MHD4-46

Product Details anti-DLL4 Antibody

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: delta-Like Protein 4

Background: Delta-like protein 4 (DLL4) is a type I transmembrane protein whose extracellular domain contains a DSL domain and eight tandem EGF repeats. After binding of its ligands Notch 1 and Notch 4, the extracellular and cytoplasmic domains are cleaved and the cytoplasmic domain is translocated into the nucleus. DLL4 is expressed in the vascular endothelium, neural epithelium, adrenal cortex, spleen, and lymph nodes. It is also highly expressed in some types of bladder, breast, and renal carcinomas. DLL4 is critical in vascular development and homeostasis.

Pathways: Notch Signaling