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IL-31 antibody

IL31 Reactivity: Mouse BCA Host: Rat Monoclonal 1C2B07 unconjugated
Catalog No. ABIN2665157
  • Target See all IL-31 (IL31) Antibodies
    IL-31 (IL31) (Interleukin 31 (IL31))
    Reactivity
    • 57
    • 9
    • 9
    Mouse
    Host
    • 52
    • 18
    Rat
    Clonality
    • 52
    • 18
    Monoclonal
    Conjugate
    • 32
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-31 antibody is un-conjugated
    Application
    • 38
    • 30
    • 22
    • 14
    • 14
    • 14
    • 10
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Biochemical Assay (BCA)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    1C2B07
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product IL31 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IL-31 (IL31) (Interleukin 31 (IL31))
    Alternative Name
    IL-31 (IL31 Products)
    Synonyms
    IL-31 antibody, 1700013B14Rik antibody, IL31 antibody, interleukin 31 antibody, IL31 antibody, Il31 antibody
    Background
    IL-31, mainly produced by activated CD4+ T cells, is a helical cytokine belonging to the gp130/IL-6 cytokine family. IL-31 is closely related in structure to IL-6, IL-11, and IL-27. Binding of IL-31 to its receptor activates JAK/STAT, PI3K/AKT, and MAPK pathways. IL-31 acts on a broad range of immune and non-immune cells and thus possesses potential pleiotropic physiological functions, such as regulating hematopoiesis and immune response. Transgenic mice overexpressing IL-31 developed severe dermatitis, indicating that IL-31 is involved in skin immunity.
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