Nerve Growth Factor antibody

Catalog No. ABIN2665291

The Mouse Monoclonal anti-Nerve Growth Factor antibody (Clone JKmNGF-1) (ABIN2665291) specifically detects Nerve Growth Factor in FACS and BR. The antibody is reactive with Human and Mouse samples.

Quick Overview for Nerve Growth Factor antibody (ABIN2665291)

Target: Nerve Growth Factor (NGF)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Nerve Growth Factor antibody is un-conjugated

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Clone: JKmNGF-1

Product Details anti-Nerve Growth Factor Antibody

Cross-Reactivity (Details): Mouse, Human, 2.5S, 7S, and β-NGF forms.

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1, IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for Nerve Growth Factor

Target: Nerve Growth Factor (NGF)

Alternative Name: NGF

Background: Nerve growth factor (NGF) is a small secreted protein that is important for the growth, maintenance, and survival of certain target neurons (nerve cells). NGF consists of three types of subunits, α, β and γ, which specifically interact to form a 7S, 130,000 Molecular weight complex. This complex contains two identical 118-amino acid β-chains, which are solely responsible for nerve growth stimulating activity of NGF. NGF is essential for the development and phenotypic maintenance of neurons in the peripheral nervous system (PNS) and for the functional integrity of cholinergic neurons in the central nervous system (CNS).

Pathways: Regulation of Cell Size