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Siglec H antibody

Reactivity: Mouse ICFC Host: Rat Monoclonal 551 unconjugated
Catalog No. ABIN2665359
  • Target See all Siglec H products
    Siglec H
    Reactivity
    Mouse
    Host
    • 8
    Rat
    Clonality
    • 8
    Monoclonal
    Conjugate
    • 4
    • 3
    • 1
    This Siglec H antibody is un-conjugated
    Application
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Intracellular Flow Cytometry (ICFC)
    Characteristics
    The Siglec-H is a member of CD33-related Siglec family which mostly expressed in the innate immune system. Siglec-H is reported to be specifically expressed on plasmacytoid dendritic cells. Siglec-H depends on adaptor protein DAP 12 (DNAX-activating protein of 12 kD) for surface expression and signal transduction. Cross-linking with this antibody can selectively inhibit interferon-alpha production by IPCs following TLR9 ligation.
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    551
    Isotype
    IgG1, IgG1 kappa
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    Siglec H
    Abstract
    Siglec H Products
    Synonyms
    6430529G09Rik antibody, Siglec-H antibody, sialic acid binding Ig-like lectin H antibody, Siglech antibody
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