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DDX58 antibody

DDX58 Reactivity: Mouse FACS Host: Rat Monoclonal SS1A unconjugated
Catalog No. ABIN2666363
  • Target See all DDX58 Antibodies
    DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
    Reactivity
    • 64
    • 41
    • 17
    • 2
    • 1
    Mouse
    Host
    • 59
    • 8
    • 1
    Rat
    Clonality
    • 61
    • 7
    Monoclonal
    Conjugate
    • 35
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DDX58 antibody is un-conjugated
    Application
    • 61
    • 19
    • 14
    • 14
    • 14
    • 11
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    SS1A
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product DDX58 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Upon receipt, store undiluted between 2°C and 8°C.
  • Target
    DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
    Alternative Name
    RIG-1 (DDX58 Products)
    Synonyms
    RIG-I antibody, RIGI antibody, RLR-1 antibody, 6430573D20Rik antibody, C330021E21 antibody, RHIV-1 antibody, RIG-1 antibody, DExD/H-box helicase 58 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 antibody, DEXD/H-box helicase 58 antibody, DDX58 antibody, Ddx58 antibody
    Background
    RIG-1/DDX58(Retinoic acid-inducible gene 1 protein/ DEAD-box protein 58) is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARD domains, a helicase ATP-binding domain and a helicase C-terminal domain. Predicted molecular weight approximately 107 kD. RIG-1 has an essential function in double-stranded RNA-induced innate antiviral responses. RIG-1 and MDA5 (melanoma differentiation-associated gene 5) are key intracellular receptors that sense intracellular viral infection and trigger a signal forinnate antiviral responses including the production of typeI IFN. Clone SS1A has been shown to be useful for western blotting of the mouse RIG-1 protein.
    Pathways
    Activation of Innate immune Response, Hepatitis C
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