SIK2 antibody
Quick Overview for SIK2 antibody (ABIN2666364)
Target
See all SIK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- The antibody was purified by affinity chromatography.
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Isotype
- IgG1 kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Upon receipt, store undiluted between 2°C and 8°C.
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- SIK2 (Salt-Inducible Kinase 2 (SIK2))
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Alternative Name
- SIK2
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Background
- SIK2 (Salt inducible kinase 2) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and AMP-activated protein kinase (AMPK) subfamily, predicted molecular weight 104 kD. SIK2 is found in adipocytes and might be involved in metabolic regulation in adipose tissue. Sik2 phosphorylates ser794 of human insulin receptor substrate-1 (IRS1) in insulin-stimulated adipocytes, playing important roles in modulating the insulin-signaling cascade of adipocytes. Clone S15G10 has been shown to be useful for western blotting, immunoprecipitation, and immunoflorence staining of human SIK2 protein.
Target
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