SND1 antibody

Catalog No. ABIN2668261

There are 2+ publications for this product available. The Mouse Monoclonal anti-SND1 antibody is suitable to detect SND1 in samples from Human and Mouse. It has been validated for WB, IHC, IF, IP and ICC.

Quick Overview for SND1 antibody (ABIN2668261)

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This SND1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: SN4-1

Product Details anti-SND1 Antibody

Purpose: SND1 antibody (mAb) (Clone SN4-1)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against a recombinant protein corresponding to amino acids 505 - 674 of human SND1.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-SND1 antibody (ABIN2668261)

Fashe, Saarikettu, Isomäki, Yang, Silvennoinen: "Expression analysis of Tudor-SN protein in mouse tissues." in: Tissue & cell, Vol. 45, Issue 1, pp. 21-31, (2013) (PubMed).

Saarikettu, Ovod, Vuoksio, Grönholm, Yang, Silvennoinen: "Monoclonal antibodies against human Tudor-SN." in: Hybridoma (2005), Vol. 29, Issue 3, pp. 231-6, (2010) (PubMed).

Target Details for SND1

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Alternative Name: SND1

Background: SND1 (staphylococcal nuclease and tudor domain containing 1) functions as a transcriptional coactivator and a modulator of RNA metabolism. As a transcriptional coactivator, it acts as a bridging factor between STAT6 and the basal transcription factors, plays a role in PIM1 regulation of MYB activity and is a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). SND-1 has been identified as part of the RISC complex (RNA-induced silencing complex) and interacts with Ago-2. It is involved in the degradation of hyper-edited inosine containing microRNA precursors as part of the RNA interference pathway.

Molecular Weight: 115 kDa

Gene ID: 27044

NCBI Accession: NP_055205