PARP1 antibody (C-Term)

Catalog No. ABIN7278745

This Rabbit Polyclonal antibody specifically detects PARP1 in WB and ChIP. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for PARP1 antibody (C-Term) (ABIN7278745)

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP1 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Product Details anti-PARP1 Antibody

Binding Specificity: C-Term

Purification: None

Immunogen: This PARP-1 C-terminal antibody was raised against a His-tagged fusion protein corresponding to the C-terminal half of human PARP-1 was used to generate this PARP-1 antibody.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-PARP1 antibody (ABIN7278745)

Ratnakumar, Duarte, LeRoy, Hasson, Smeets, Vardabasso, Bönisch, Zeng, Xiang, Zhang, Li, Wang, Hake, Schermelleh, Garcia, Bernstein: "ATRX-mediated chromatin association of histone variant macroH2A1 regulates ?-globin expression." in: Genes & development, Vol. 26, Issue 5, pp. 433-8, (2012) (PubMed).

Target Details for PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Alternative Name: PARP-1

Molecular Weight: 120 kDa

Gene ID: 142

Pathways: Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location