Histone H2A Variant H2A.Z, Pht1 (PHT1) (C-Term) antibody

Catalog No. ABIN2668341

This Rabbit Polyclonal antibody specifically detects Histone H2A Variant H2A.Z, Pht1 in WB. It exhibits reactivity toward Schizosaccharomyces pombe.It has been mentioned in 1 publication

Quick Overview for Histone H2A Variant H2A.Z, Pht1 (PHT1) (C-Term) antibody (ABIN2668341)

Target: Histone H2A Variant H2A.Z, Pht1 (PHT1)

Reactivity: Schizosaccharomyces pombe

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Purpose: Pht1 / Histone H2A.Z antibody (pAb) (H2AZ)

Purification: Affinity Purified

Immunogen: This Pht1 / H2AZ antibody was raised against a peptide corresponding to the C-terminus of Pht1, the histone H2A variant in S. pombe.

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:1,000 dilution

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References

Tapia-Alveal, Lin, Yeoh, Jabado, OConnell: "H2A.Z-dependent regulation of cohesin dynamics on chromosome arms." in: Molecular and cellular biology, Vol. 34, Issue 11, pp. 2092-104, (2014) (PubMed).

Target Details

Target: Histone H2A Variant H2A.Z, Pht1 (PHT1)

Alternative Name: Pht1 / Histone H2A.Z

Target Type: Chemical

Background: Pht1 is the S. pombe homolog of histone H2AZ and is involved in transcriptional regulation and chromosome architecture. It is also implicated in suppressing the accumulation of anti-sense transcripts through interaction with RNAi machinery and heterochromatin proteins.

Molecular Weight: 15 kDa

NCBI Accession: NP_595630