TWIST1 antibody

Catalog No. ABIN2668516

The Mouse Monoclonal anti-TWIST1 antibody has been validated for WB, IHC, ICC and IF. It is suitable to detect TWIST1 in samples from Human and Mouse. There are 5+ publications available.

Quick Overview for TWIST1 antibody (ABIN2668516)

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TWIST1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-TWIST1 Antibody

Purification: Protein G Chromatography

Immunogen: This TWIST antibody was raised against a recombinant protein corresponding to full-length mouse TWIST.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -80 °C

Storage Comment: Antibodies in solution can be stored at -80 °C for 2 years.

Expiry Date: 6 months

References for anti-TWIST1 antibody (ABIN2668516)

Ezponda, Popovic, Shah, Martinez-Garcia, Zheng, Min, Will, Neri, Kelleher, Yu, Licht: "The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer." in: Oncogene, Vol. 32, Issue 23, pp. 2882-90, (2013) (PubMed).

Casas, Kim, Bendesky, Ohno-Machado, Wolfe, Yang: "Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis." in: Cancer research, Vol. 71, Issue 1, pp. 245-54, (2011) (PubMed).

Eckert, Lwin, Chang, Kim, Danis, Ohno-Machado, Yang: "Twist1-induced invadopodia formation promotes tumor metastasis." in: Cancer cell, Vol. 19, Issue 3, pp. 372-86, (2011) (PubMed).

Kida, Asahina, Teraoka, Gitelman, Sato: "Twist relates to tubular epithelial-mesenchymal transition and interstitial fibrogenesis in the obstructed kidney." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 55, Issue 7, pp. 661-73, (2007) (PubMed).

Gitelman: "Twist protein in mouse embryogenesis." in: Developmental biology, Vol. 189, Issue 2, pp. 205-14, (1997) (PubMed).

Target Details for TWIST1

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Alternative Name: TWIST

Molecular Weight: 21 kDa

Gene ID: 7291

Pathways: p53 Signaling, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity