KLF6 antibody (AA 28-199)

Catalog No. ABIN2668584

This Mouse Monoclonal antibody specifically detects KLF6 in WB and IHC. It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for KLF6 antibody (AA 28-199) (ABIN2668584)

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLF6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 2A2

Product Details anti-KLF6 Antibody

Binding Specificity: AA 28-199

Purpose: KLF6 antibody (mAb) (Clone 2A2)

Purification: Protein A Chromatography

Immunogen: This KLF6 antibody was raised against a recombinant protein corresponding to amino acids 28-199 of human Kruppel-like factor 6 (KLF6).

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-KLF6 antibody (ABIN2668584)

Narla, DiFeo, Fernandez, Dhanasekaran, Huang, Sangodkar, Hod, Leake, Friedman, Hall, Chinnaiyan, Gerald, Rubin, Martignetti: "KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis." in: The Journal of clinical investigation, Vol. 118, Issue 8, pp. 2711-21, (2008) (PubMed).

Narla, DiFeo, Yao, Banno, Hod, Reeves, Qiao, Camacho-Vanegas, Levine, Kirschenbaum, Chan, Friedman, Martignetti: "Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread." in: Cancer research, Vol. 65, Issue 13, pp. 5761-8, (2005) (PubMed).

Target Details for KLF6

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Alternative Name: KLF6

Background: KLF6 (Kruppel-like factor 6, BCD1, COPEB, CPBP, ST12) is a transcriptional activator (By similarity). Binds a GC box motif. Could play a role in B-cell growth and development. This antibody recognizes the 33 kDa wild type KLF6, 26 kDa KLF6 splice variant and the 30 kDa KLF6 splice variant.

Molecular Weight: 33 kDa

Gene ID: 1316

NCBI Accession: NP_001291