PIM2 antibody

Catalog No. ABIN2668602

This Rat Monoclonal antibody specifically detects PIM2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for PIM2 antibody (ABIN2668602)

Target: PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This PIM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CHU61

Product Details anti-PIM2 Antibody

Purpose: PIM2 antibody (mAb) (Clone CHU61)

Purification: Protein G Chromatography

Immunogen: This PIM2 antibody was raised against a recombinant protein corresponding to human PIM2.

Isotype: IgG2a

Application Details

Application Notes: IHC: 2 μg/mL dilution WB: 0.5 - 2 μg/mL dilution The antibody is suitable for IHC on paraffin sections. Frozen sections are not recommended. This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91239.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified rat IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for PIM2

Target: PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))

Alternative Name: PIM2

Background: PIM2 is a serine/threonine protein kinase in the CAMK family. PIM2 promotes cell survival in response to a variety of proliferative signals through activation of the I-kB kinase/NF-kB pathway. It also inhibits apoptosis through the phosphorylation of BAD. PIM2 has been implicated in the transformation of both T and B lymphocytes and is highly expressed in human leukemia and lymphomas, as well as adenocarcinomas and hepatocellular carcinomas.

Molecular Weight: 37 kDa

Gene ID: 11040

NCBI Accession: NP_006866