PAX9 antibody

Catalog No. ABIN2667996

There are 2+ publications for this product available. The Rat Monoclonal anti-PAX9 antibody is suitable to detect PAX9 in samples from Human. It has been validated for WB and IHC.

Quick Overview for PAX9 antibody (ABIN2667996)

Target: PAX9 (Paired Box 9 (PAX9))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This PAX9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 7C2

Product Details anti-PAX9 Antibody

Purpose: PAX9 antibody (mAb) (Clone 7C2)

Purification: Protein G Chromatography

Immunogen: This PAX9 antibody was raised against a recombinant protein corresponding to amino acids to 263-342 of mouse PAX9 protein.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-PAX9 antibody (ABIN2667996)

Kist, Watson, Wang, Cairns, Miles, Reid, Peters: "Reduction of Pax9 gene dosage in an allelic series of mouse mutants causes hypodontia and oligodontia." in: Human molecular genetics, Vol. 14, Issue 23, pp. 3605-17, (2005) (PubMed).

Gerber, Richter, Kremmer, Adamski, Höfler, Balling, Peters: "Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus." in: The Journal of pathology, Vol. 197, Issue 3, pp. 293-7, (2002) (PubMed).

Target Details for PAX9

Target: PAX9 (Paired Box 9 (PAX9))

Alternative Name: PAX9

Background: PAX9 (PAX-9, Paired box protein 9) is a sequence specific DNA binding transcription factor required for normal development of the thymus, parathyroid glands, teeth, portions of the skull and larynx as well as distal limbs. PAX9 is a member of the paired box (PAX) family of transcription factors, which typically contain a paired box domain, a paired type homeodomain and an octapeptide sequence.

Molecular Weight: 38 kDa

Gene ID: 5083

NCBI Accession: NP_035171