CXXC4 antibody (N-Term)

Catalog No. ABIN2668637

The Rabbit Polyclonal anti-CXXC4 antibody (ABIN2668637) specifically detects CXXC4 in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for CXXC4 antibody (N-Term) (ABIN2668637)

Target: CXXC4 (CXXC Finger Protein 4 (CXXC4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXXC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CXXC4 Antibody

Binding Specificity: N-Term

Purpose: Cxxc4 antibody (pAb)

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within the N-terminal region of mouse Cxxc4.

Isotype: IgG

Application Details

Application Notes: WB: 1:1,000 - 1:2,500 dilution The addition of 0.1 % Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for CXXC4

Target: CXXC4 (CXXC Finger Protein 4 (CXXC4))

Alternative Name: Cxxc4

Background: Cxxc4 (CXXC Finger Protein 4) acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1 and has been implicated in malignant renal cell carcinoma and colonic villous adenoma. Recently, Cxxc4 has been shown to be involved in the regulation of DNA demethylation. It binds to unmethylated CpGs in DNA and is involved in TET2 downregulation.

Molecular Weight: 42 kDa

Gene ID: 319478

NCBI Accession: NP_001004367