FOXA2 antibody (AA 7-86)

Catalog No. ABIN2668683

This Rabbit Polyclonal antibody specifically detects FOXA2 in WB and IHC. It exhibits reactivity toward Human and Rat.It has been mentioned in 1 publication

Quick Overview for FOXA2 antibody (AA 7-86) (ABIN2668683)

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FOXA2 Antibody

Binding Specificity: AA 7-86

Purpose: HNF-3b / FOXA2 antibody (pAb)

Purification: Unpurified

Immunogen: This HNF-3b / FOXA2 antibody was raised against a recombinant protein corresponding to amino acids 7-86 of rat HNF-3b /FOXA2.

Application Details

Application Notes: WB: 1:2,000 - 1:5,000 dilution

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-FOXA2 antibody (ABIN2668683)

Wan, Kaestner, Ang, Ikegami, Finkelman, Stahlman, Fulkerson, Rothenberg, Whitsett: "Foxa2 regulates alveolarization and goblet cell hyperplasia." in: Development (Cambridge, England), Vol. 131, Issue 4, pp. 953-64, (2004) (PubMed).

Target Details for FOXA2

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Alternative Name: HNF-3beta / FOXA2

Background: HNF-3b (Hepatocyte nuclear factor 3 beta, forkhead box A2, FoxA2) is a homeodomain containing transcription factor and is a member of the Hepatocyte Nuclear Factor family (HNF-1a, HNF-1b, HNF-3a, HNF-3b, HNF-3g, HNF-4a, HNF-4g, HNF-6a and HNF-6b), whose members regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3 members bind to DNA as monomers using a winged helix DNA-binding domain. HNF-3a and HNF-3g have also been shown to be involved in gastrulation events such as body axis formation.

Molecular Weight: 50 kDa

Gene ID: 3170

NCBI Accession: NP_036875

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process