Retinoid X Receptor gamma antibody

Catalog No. ABIN2668700

Cited in 2+ publications. The Mouse Monoclonal anti-Retinoid X Receptor gamma antibody (Clone 12RX-2D3) (ABIN2668700) specifically detects Retinoid X Receptor gamma in WB, IHC and SSA. The antibody is reactive with Human samples.

Quick Overview for Retinoid X Receptor gamma antibody (ABIN2668700)

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoid X Receptor gamma antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Supershift Assay (SSA)

Clone: 12RX-2D3

Product Details anti-Retinoid X Receptor gamma Antibody

Purpose: RXR-gamma antibody (mAb) (Clone 12RX-2D3)

Purification: Protein G Chromatography

Immunogen: This RXR-gamma antibody was raised against a peptide within the D-region of mouse RXR-gamma.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-Retinoid X Receptor gamma antibody (ABIN2668700)

Reichrath, Mittmann, Kamradt, Müller: "Expression of retinoid-X receptors (-alpha,-beta,-gamma) and retinoic acid receptors (-alpha,-beta,-gamma) in normal human skin: an immunohistological evaluation." in: The Histochemical journal, Vol. 29, Issue 2, pp. 127-33, (1997) (PubMed).

Rochette-Egly, Lutz, Pfister, Heyberger, Scheuer, Chambon, Gaub: "Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies." in: Biochemical and biophysical research communications, Vol. 204, Issue 2, pp. 525-36, (1994) (PubMed).

Target Details for Retinoid X Receptor gamma

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Alternative Name: RXR-gamma

Background: RXR-g (retinoid X receptor gamma, NR2B3) is a member of the nuclear receptors superfamily, specifically those involved in mediating the effects of retinoic acid (RA). This receptor forms heterodimers with the RAR (retinoic acid receptor), TR (thyroid hormone receptor) and the VDR (vitamin D receptor), increasing both DNA binding and transcriptional function on their respective response elements.

Molecular Weight: 51 kDa

Gene ID: 20183

NCBI Accession: NP_033133

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway