MITF antibody (N-Term)

Catalog No. ABIN2668714

The Mouse Monoclonal anti-MITF antibody has been validated for WB, IF, IP, ICC, EMSA, ChIP-seq and ChIP. It is suitable to detect MITF in samples from Human. There are 3+ publications available.

Quick Overview for MITF antibody (N-Term) (ABIN2668714)

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MITF antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Electrophoretic Mobility-Shift Assay (EMSA), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP)

Product Details anti-MITF Antibody

Binding Specificity: N-Term

Purification: Protein G Chromatography

Immunogen: This MITF antibody was raised against an N-terminal fragment of human MITF.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-MITF antibody (ABIN2668714)

Wellbrock, Marais: "Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation." in: The Journal of cell biology, Vol. 170, Issue 5, pp. 703-8, (2005) (PubMed).

Du, Miller, Widlund, Horstmann, Ramaswamy, Fisher: "MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma." in: The American journal of pathology, Vol. 163, Issue 1, pp. 333-43, (2003) (PubMed).

Hemesath, Price, Takemoto, Badalian, Fisher: "MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes." in: Nature, Vol. 391, Issue 6664, pp. 298-301, (1998) (PubMed).

Target Details for MITF

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Alternative Name: MITF

Molecular Weight: 52-56 kDa

Gene ID: 4286

Pathways: Chromatin Binding