IKZF3 antibody (N-Term)

Catalog No. ABIN2668825

There is 1 publication for this product available. The Mouse Monoclonal anti-IKZF3 antibody is suitable to detect IKZF3 in samples from Mouse. It has been validated for WB and ChIP.

Quick Overview for IKZF3 antibody (N-Term) (ABIN2668825)

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This IKZF3 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Clone: 8B2

Product Details anti-IKZF3 Antibody

Binding Specificity: N-Term

Purpose: Aiolos antibody (mAb) (Clone 8B2)

Purification: Protein G Chromatography

Immunogen: This Aiolos antibody was raised against the N-terminal half of mouse Aiolos protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-IKZF3 antibody (ABIN2668825)

Thompson, Cobb, Sabbattini, Meixlsperger, Parelho, Liberg, Taylor, Dillon, Georgopoulos, Jumaa, Smale, Fisher, Merkenschlager: "Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits." in: Immunity, Vol. 26, Issue 3, pp. 335-44, (2007) (PubMed).

Target Details for IKZF3

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Alternative Name: Aiolos

Background: Aiolos (also known as IKZF3, Ikaros family zinc finger 3 and ZNFN1A3) belongs to a family of zinc-finger proteins that also include Ikaros and Helios. Aiolos is a transcription factor that is important in the regulation of lymphocyte proliferation and differentiation, which is preferentially expressed in peripheral blood leukocytes, spleen and thymus tissue. Both Ikaros and Aiolos can also participate in chromatin remodeling.

Molecular Weight: 70 kDa

Gene ID: 22780

NCBI Accession: NP_035901