PROX1 antibody (AA 547-737)

Catalog No. ABIN2668928

Cited in 1 publication. The Mouse Monoclonal anti-PROX1 antibody (Clone 4G10) (ABIN2668928) specifically detects PROX1 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for PROX1 antibody (AA 547-737) (ABIN2668928)

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PROX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 4G10

Product Details anti-PROX1 Antibody

Binding Specificity: AA 547-737

Purpose: Prox1 antibody (mAb) (Clone 4G10)

Purification: Protein G Chromatography

Immunogen: This Prox1 antibody was raised against a recombinant protein corresponding to amino acids 547-737 of human Prox1.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-PROX1 antibody (ABIN2668928)

Chen, Patel, Cain, Duncan: "Production of monoclonal antibodies against Prox1." in: Hybridoma (2005), Vol. 25, Issue 1, pp. 27-33, (2006) (PubMed).

Target Details for PROX1

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Alternative Name: Prox1

Background: Prox1 (Prospero-like homeobox protein 1) is a sequence-specific DNA binding transcription factor. Prox1 controls lymphatic endothelial and retinal progenitor cell differentiation, as well as development of the liver and lens of the eye. Required for lymphatic endothelial cells specification and the formation of lymphatic vessels.

Molecular Weight: 90 kDa

Gene ID: 5629

NCBI Accession: NP_002754

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation