FOXP1 antibody (AA 495-578)

Catalog No. ABIN2668950

This Mouse Monoclonal antibody specifically detects FOXP1 in WB, ChIP, SSA and ChIP-seq. It exhibits reactivity toward Mouse. It has been mentioned in 2+ publications

Quick Overview for FOXP1 antibody (AA 495-578) (ABIN2668950)

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXP1 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Supershift Assay (SSA), ChIP DNA-Sequencing (ChIP-seq)

Clone: 1G1

Product Details anti-FOXP1 Antibody

Binding Specificity: AA 495-578

Purpose: FOXP1 antibody (mAb) (Clone 1G1)

Purification: Protein A Chromatography

Immunogen: This FOXP1 antibody was raised against a recombinant protein corresponding to amino acids 495-578 of mouse FOXP1. This antibody detects three isoforms.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-FOXP1 antibody (ABIN2668950)

Hu, Wang, Borde, Nardone, Maika, Allred, Tucker, Rao: "Foxp1 is an essential transcriptional regulator of B cell development." in: Nature immunology, Vol. 7, Issue 8, pp. 819-26, (2006) (PubMed).

Wang, Lin, Li, Tucker: "Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors." in: The Journal of biological chemistry, Vol. 278, Issue 27, pp. 24259-68, (2003) (PubMed).

Target Details for FOXP1

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Alternative Name: FOXP1

Background: FOXP1 (forkhead box P1) is a transcriptional repressor and belongs to subfamily P of the forkhead box (FOX) transcription factor family. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B-cell development (By similarity).

Molecular Weight: 95, 70 & 50 kDa

Gene ID: 108655

NCBI Accession: NP_444432

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response