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HIV-1 Tat antibody (Biotin)

Reactivity: Human Immunodeficiency Virus (HIV) ELISA, WB, IF Host: Rabbit Polyclonal Biotin
Catalog No. ABIN2669357
  • Target See all HIV-1 Tat Antibodies
    HIV-1 Tat
    Reactivity
    Human Immunodeficiency Virus (HIV)
    Host
    • 11
    • 7
    • 1
    Rabbit
    Clonality
    • 11
    • 8
    Polyclonal
    Conjugate
    • 14
    • 3
    • 2
    This HIV-1 Tat antibody is conjugated to Biotin
    Application
    • 17
    • 17
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF)
    Specificity
    The antibody detects HIV1 tat protein and GST tat fusion protein. HIVI tat protein in sera or plasma and in cell culture supernatant
    Characteristics
    Tat is a regulatory protein of HIV-1 virus, well conserved among different isolates. Tat is produced early after infection and it's essential for virus replication and infectivity. Tat protein is also immunogenic and antibodies (Ab) against tat have been found to correlate with delayed disease progression and may exert protective effects by inhibiting both HIV-1 replication and the effects of extracellular tat. Moreover, tat is efficiently taken up by monocyte-derived dendritic cells, promotes their maturation and antigen presenting since it enters the major histocompatibility complex class I pathway. Finally, murine vaccination with a biologically active tat protein has been shown to be safe, immunogenic and elicits anti-tat neutralizing Ab and CTL.
    Purification
    Purified by protein A affinity chromatography and conjugated by NHS-biotin.
    Immunogen
    Purified recombinant protein HIV-I tat expressed in E. coli
    Top Product
    Discover our top product HIV-1 Tat Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied in PBS and 0.05 % v/v glycerol
    Storage
    4 °C
  • Target
    HIV-1 Tat
    Alternative Name
    HIV1 Tat (HIV-1 Tat Products)
    Target Type
    Viral Protein
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