BACE1 antibody (AA 112-324)

Catalog No. ABIN2682977

This anti-BACE1 antibody is a Mouse Monoclonal antibody detecting BACE1 in WB, ELISA, ICC and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for BACE1 antibody (AA 112-324) (ABIN2682977)

Target: BACE1 (Beta-secretase 1 (BACE1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 3C1C3

Product Details anti-BACE1 Antibody

Binding Specificity: AA 112-324

Purpose: BACE1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: BACE1

Background: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 55.7 kDa

Gene ID: 23621

UniProt: P56817