Coagulation Factor VIIa antibody

Catalog No. ABIN2688653

The Rabbit Polyclonal anti-Coagulation Factor VIIa antibody has been validated for ELISA, PtA and InhA. It is suitable to detect Coagulation Factor VIIa in samples from Human.

Quick Overview for Coagulation Factor VIIa antibody (ABIN2688653)

Target: Coagulation Factor VIIa (FV7a)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: ELISA, Prothrombin Assay (PtA), Inhibition Assay (InhA)

Product Details anti-Coagulation Factor VIIa Antibody

Specificity: No significant difference in binding to Factor VII and Factor VIIa

Cross-Reactivity (Details): Not reactive in: no confirmed exceptions from predicted reactivity known in the moment

Predicted Reactivity: primates

Characteristics: Expected / apparent Molecular Weight of the Antigene: 52 kDa (this is MW of Factor VIIa)

Purification: affinity purified

Immunogen: Recombinant human Factor VIIa (NovoSeven ®, Novo Nordisk A/S Denmark)

Application Details

Application Notes: 1: 15 000 (I-ELISA), 14 μg/mL (IL)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μL of sterile water

Buffer: PBS pH 7.4

Handling Advice: Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Once reconstituted make aliquots to avoid repreated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them, to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.

Target Details for Coagulation Factor VIIa

Target: Coagulation Factor VIIa (FV7a)

Alternative Name: Coagulation factor VIIa (FVIIa)

Background: Factor VIIa (FVIIa) is a key serine protease involved in the initiation of the coagulation cascade. FVIIa requires tissue factor (TF), a membrane bound protein, as an essential cofactor for maximal activity towards its biological substrates Factor X, Factor IX and Factor VII (FVII).

Molecular Weight: 52 kDa (this is MW of Factor VIIa)

UniProt: Q9FI56, Q9SXJ7