Coagulation Factor VIIa antibody

Catalog No. ABIN2688653

The Rabbit Polyclonal anti-Coagulation Factor VIIa antibody is suitable to detect Coagulation Factor VIIa in samples from Human. It has been validated for ELISA and PtA.

Quick Overview for Coagulation Factor VIIa antibody (ABIN2688653)

Target: Coagulation Factor VIIa (FV7a)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coagulation Factor VIIa antibody is un-conjugated

Application: ELISA, Prothrombin Assay (PtA)

Product Details anti-Coagulation Factor VIIa Antibody

Purpose: Anti-FVIIa | Coagulation factor VIIa (50 μg)

Specificity: No significant difference in binding to Factor VII and Factor VIIa

Cross-Reactivity (Details): Human
Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Predicted Reactivity: Primates

Purification: Immunogen affinity purified

Immunogen: Recombinant human Factor VIIa (NovoSeven ®

Application Details

Application Notes: 1 : 15 000 (I-ELISA), 14 μg/mL (IL)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μL of sterile water

Buffer: Immunogen affinity purified IgG in PBS pH 7.4.

Storage: -20 °C

Storage Comment: Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them, to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Target Details for Coagulation Factor VIIa

Target: Coagulation Factor VIIa (FV7a)

Alternative Name: Coagulation factor VIIa (FVIIa)

Background:

Background: Factor VIIa (FVIIa) is a key serine protease involved in the initiation of the coagulation cascade. FVIIa requires tissue factor (TF), a membrane bound protein, as an essential cofactor for maximal activity towards its biological substrates Factor X, Factor IX and Factor VII (FVII).

Additional information: No significant difference in binding to Factor VII and Factor VIIa.Antibody is purified to total IgG fraction, followed by purification on specific FVIIa column.

Molecular Weight: 52 kDa (this is MW of Factor VIIa)

Gene ID: 835165

UniProt: Q9FI56, Q9SXJ7