Coagulation Factor VIIa antibody

Catalog No. ABIN2688653

This Rabbit Polyclonal antibody specifically detects Coagulation Factor VIIa in PtA and ELISA. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for Coagulation Factor VIIa antibody (ABIN2688653)

Target: Coagulation Factor VIIa (FV7a)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Prothrombin Assay (PtA), ELISA

Product Details anti-Coagulation Factor VIIa Antibody

Purpose: Anti-FVIIa | Coagulation factor VIIa (500 μg)

Cross-Reactivity (Details): Human
Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Predicted Reactivity: Primates

Purification: Immunogen affinity purified

Immunogen: Recombinant human Factor VIIa (NovoSeven ®

Application Details

Application Notes: 1 : 15 000 (I-ELISA)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 500 μL of sterile water

Buffer: Immunogen affinity purified IgG in PBS pH 7.4.

Storage: -20 °C

Storage Comment: Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them, to avoid any losses that might occur from material adhering to the cap or sides of the tube.

References for anti-Coagulation Factor VIIa antibody (ABIN2688653)

Prins, van Heerden, Olmos, Kunert, Foyer: "Cysteine proteinases regulate chloroplast protein content and composition in tobacco leaves: a model for dynamic interactions with ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) vesicular bodies." in: Journal of experimental botany, Vol. 59, Issue 7, pp. 1935-50, (2008) (PubMed).

Target Details for Coagulation Factor VIIa

Target: Coagulation Factor VIIa (FV7a)

Alternative Name: Coagulation factor VIIa (FVIIa)

Background:

Background: Factor VIIa (FVIIa) is a key serine protease involved in the initiation of the coagulation cascade. FVIIa requires tissue factor (TF), a membrane bound protein, as an essential cofactor for maximal activity towards its biological substrates Factor X, Factor IX and Factor VII (FVII).

Additional information: No significant difference in binding to Factor VII and Factor VIIa.Antibody is purified to total IgG fraction, followed by purification on specific FVIIa column.

Molecular Weight: 52 kDa

Gene ID: 835165

UniProt: Q9FI56, Q9SXJ7