LAMP1 antibody (Biotin)

Catalog No. ABIN2688885

The Mouse Monoclonal anti-LAMP1 antibody has been validated for ICS. It is suitable to detect LAMP1 in samples from Human. There are 2+ publications available.

Quick Overview for LAMP1 antibody (Biotin) (ABIN2688885)

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAMP1 antibody is conjugated to Biotin

Application: Intracellular Staining (ICS)

Clone: H4A3

Product Details anti-LAMP1 Antibody (Biotin)

Brand: BD Pharmingen™

Characteristics: Reacts with the heavily glycosylated 110 kDa lysosomal-associated membrane protein, LAMP-1. LAMP-1 is a widely expressed intracellular antigen. It is also expressed on the surface of activated platelets, PHA-activated lymphocytes and some tumor cell lines, including U937 and KG1a. LAMP-1 has been shown to be a ligand for E-selectin-mediated cell adhesion. LAMP-1 and LAMP-2 (CD107b) are carriers for poly-N-acetyllactosamines, and are able to display sialyl Le[x] termini. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of permeabilized jurkat cells analyzed on a FACScan

BD Pharmingen™ Biotin Mouse Anti-Human CD107a - Biotin - Clone H4A3 - Isotype Mouse IgG1, κ - Reactivity Hu - 100 Tests

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Sample Volume: 20 μL

Restrictions: For Research Use only

Handling

Buffer: Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

References for anti-LAMP1 antibody (Biotin) (ABIN2688885)

Febbraio, Silverstein: "Identification and characterization of LAMP-1 as an activation-dependent platelet surface glycoprotein." in: The Journal of biological chemistry, Vol. 265, Issue 30, pp. 18531-7, (1990) (PubMed).

Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

Target Details for LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Alternative Name: CD107a

Background: Synonyms: LAMP-1

Pathways: Autophagy