IL2RG antibody (Biotin)

Catalog No. ABIN2688955

This anti-IL2RG antibody is a Rat Monoclonal antibody detecting IL2RG in FACS. Suitable for Human and Dog. This Primary Antibody has been cited in 2+ publications.

Quick Overview for IL2RG antibody (Biotin) (ABIN2688955)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reactivity: Human, Dog

Host: Rat

Clonality: Monoclonal

Conjugate: This IL2RG antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: TUGh4

Product Details anti-IL2RG Antibody (Biotin)

Brand: BD Pharmingen™

Characteristics: This antibody reacts with the 65-70 kDa common γ subunit (γc) shared by the IL-2, IL-4, IL-7, IL-9, and IL-15 receptors. The γc receptor is a glycoprotein expressed by most peripheral T and B lymphocytes, NK cells, monocytes, and granulocytes. The cytoplasmic domain of the γc chain plays an important role in cytokine-mediated signal transduction. By immunofluorescent staining and flow cytometric analysis, the TUGh4 antibody has been shown to specifically recognize human γc expressed by cell lines, including human γc gene-transfected cell lines, which are known to express the human γc chain.

BD Pharmingen™ Biotin Rat Anti-Human CD132 - Biotin - Clone TUGh4 - Isotype Rat IgG2b, κ - Reactivity Hu, Dog - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing protein stabilizer and ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-IL2RG antibody (Biotin) (ABIN2688955)

Ishii, Takeshita, Kimura, Tada, Kondo, Nakamura, Sugamura: "Expression of the IL-2 receptor gamma chain on various populations in human peripheral blood." in: International immunology, Vol. 6, Issue 8, pp. 1273-7, (1995) (PubMed).

Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

Target Details for IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: CD132

Pathways: JAK-STAT Signaling, Growth Factor Binding