CD14 antibody

Catalog No. ABIN2688969

The Mouse Monoclonal anti-CD14 antibody has been validated for FACS and IHC (fro). It is suitable to detect CD14 in samples from Human, Cynomolgus, Rhesus Monkey, Baboon and Dog. There is 1 publication available.

Quick Overview for CD14 antibody (ABIN2688969)

Target: CD14

Reactivity: Human, Cynomolgus, Rhesus Monkey, Baboon, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: M5E2

Product Details anti-CD14 Antibody

Brand: BD Pharmingen™

Characteristics: Reacts with the 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB. Profile of peripheral blood monocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD14 - Purified - Clone M5E2 - Isotype Mouse IgG2a, κ - Reactivity Hu, Bab, Cyno, Dog, Rhe - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD14 antibody (ABIN2688969)

Wright, Ramos, Tobias, Ulevitch, Mathison: "CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein." in: Science (New York, N.Y.), Vol. 249, Issue 4975, pp. 1431-3, (1990) (PubMed).

Target Details for CD14

Target: CD14

Alternative Name: CD14

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades