Cadherin 5 antibody
-
- Target See all Cadherin 5 (CDH5) Antibodies
- Cadherin 5 (CDH5)
-
Reactivity
- Mouse
-
Host
- Rat
-
Clonality
- Monoclonal
-
Conjugate
- This Cadherin 5 antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Brand
- BD Pharmingen™
- Characteristics
-
The 11D4.1 antibody reacts with mouse VE-cadherin, a member of the cadherin family. VE-cadherin is an endothelial cell-specific, homophilic adhesion molecule. It is concentrated at interendothelial cells contacts and is thought to be involved in the maintenance of cell layer integrity. In vitro and in vivo studies indicate that the 11D.4 mAb interferes with VE-cadherin-mediated intercellular adhesion. Immunohistochemical staining of CD144. Frozen sections of normal mouse small intestine were reacted with the anti-CD144 antibody. Cells expressing VE-Cadherin can be identified by the brown labeling of their cell membranes. Amplification 20X.
BD Pharmingen™ Purified Rat Anti-Mouse CD144 - Purified - Clone 11D4.1 - Isotype Rat IgG2a, κ - Reactivity Ms - 1 mL - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Immunogen
- Mouse VE-Cadherin-Ig Fusion
- Clone
- 11D4-1
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CDH5 Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 125 μg/mL
- Buffer
- Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C.
-
-
VE-cadherin antibody accelerates neutrophil recruitment in vivo." in: Journal of cell science, Vol. 110 ( Pt 5), pp. 583-8, (1997) (PubMed).
: "Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system." in: Blood, Vol. 87, Issue 2, pp. 630-41, (1996) (PubMed).
: "A novel endothelial-specific membrane protein is a marker of cell-cell contacts." in: The Journal of cell biology, Vol. 118, Issue 6, pp. 1511-22, (1992) (PubMed).
: "
-
VE-cadherin antibody accelerates neutrophil recruitment in vivo." in: Journal of cell science, Vol. 110 ( Pt 5), pp. 583-8, (1997) (PubMed).
-
- Target
- Cadherin 5 (CDH5)
- Alternative Name
- CD144 (CDH5 Products)
- Synonyms
- 7B4 antibody, AA408225 antibody, Cd144 antibody, VE-Cad antibody, VECD antibody, VEcad antibody, Vec antibody, wu:fc88a07 antibody, CD144 antibody, cadherin-5 antibody, cadherin 5 antibody, CDH5 antibody, Cdh5 antibody, cdh5 antibody
- Background
- Synonyms: VE-Cadherin, Cadherin-5
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
-