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- Target See all CD1d (CD1D) Antibodies
- CD1d (CD1D) (CD1d Molecule (CD1D))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD1d antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Brand
- BD Pharmingen™
- Characteristics
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Reacts with a glycosylated type I transmembrane α chain (43-49 kDa) non- covalently associated with β2-microglobulin. CD1d is a member of the CD1 family of molecules, which belong to the immunoglobulin superfamily. Sequence homology data classifies the CD1 Molecules into two groups. Group 1 includes CD1a, CD1b and CD1c molecules, group 2 includes CD1d molecules and their homologues in other species. CD1d is expressed on human intestinal epithelial cells (IEC). CD1d42 monoclonal antibody reacts with peripheral blood B cells coexpressing CD19 and CD45RA. It is not seen on CD3[+], or CD45RO[+] cells. Studies suggest that CD1d participates in lipid antigen presentation. Profile of peripheral blood lymphocytes analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD1d - Purified - Clone CD1d42 (also known as 42.1) - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Clone
- CD1d42
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD1D Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C.
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Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice." in: Immunological reviews, Vol. 169, pp. 31-44, (1999) (PubMed).
: "Immunolocalization of CD1d in human intestinal epithelial cells and identification of a beta2-microglobulin-associated form." in: International immunology, Vol. 11, Issue 3, pp. 383-92, (1999) (PubMed).
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Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice." in: Immunological reviews, Vol. 169, pp. 31-44, (1999) (PubMed).
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- Target
- CD1d (CD1D) (CD1d Molecule (CD1D))
- Alternative Name
- CD1d (CD1D Products)
- Synonyms
- CD1A antibody, R3 antibody, CD1D antibody, CD1D1 antibody, CD1d molecule antibody, CD1D antigen, d polypeptide antibody, CD1D antibody
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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