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PROCR antibody

PROCR Reactivity: Human FACS Host: Rat Monoclonal RCR unconjugated
Catalog No. ABIN2689080
  • Target See all PROCR Antibodies
    PROCR (Protein C Receptor, Endothelial (PROCR))
    Reactivity
    • 55
    • 13
    • 12
    • 1
    Human
    Host
    • 47
    • 11
    • 10
    Rat
    Clonality
    • 48
    • 20
    Monoclonal
    Conjugate
    • 42
    • 11
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PROCR antibody is un-conjugated
    Application
    • 49
    • 29
    • 18
    • 14
    • 11
    • 9
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Brand
    BD Pharmingen™
    Characteristics
    Reacts with endothelial cell protein C receptor (EPCR), a 25 kDa, type I transmembrane glycoprotein, expressed on endothelial cells in arteries, veins and capillaries. EPCR is also referred to as CD201. It binds protein C and augments its activation. Reports indicate that EPCR is expressed on several malignant cell lines. Malignant cell lines that express EPCR also show significant levels of protein C activation and this activation could be inhibited by anti-EPCR antibody. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of anti-CD201 (RCR-252) reactivity on ECV304 cells analyzed by flow cytometry. Second step staining with Cat. No. 554016.

    BD Pharmingen™ Purified Rat Anti-Human CD201 - Purified - Clone RCR-252 - Isotype Rat IgG1, κ - Reactivity Hu - 0.1 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    RCR
    Isotype
    IgG1 kappa
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    Discover our top product PROCR Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C.
  • Biguzzi, Merati, Liaw, Bucciarelli, Oganesyan, Qu, Gu, Fetiveau, Esmon, Mannucci, Faioni: "A 23bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function." in: Thrombosis and haemostasis, Vol. 86, Issue 4, pp. 945-8, (2001) (PubMed).

    Tsuneyoshi, Fukudome, Horiguchi, Ye, Matsuzaki, Toi, Suzuki, Kimoto: "Expression and anticoagulant function of the endothelial cell protein C receptor (EPCR) in cancer cell lines." in: Thrombosis and haemostasis, Vol. 85, Issue 2, pp. 356-61, (2001) (PubMed).

  • Target
    PROCR (Protein C Receptor, Endothelial (PROCR))
    Alternative Name
    CD201 (PROCR Products)
    Synonyms
    PROCR antibody, CCCA antibody, CCD41 antibody, EPCR antibody, AI325044 antibody, Ccca antibody, Ccd41 antibody, Epcr antibody, protein C receptor antibody, protein C receptor, endothelial antibody, PROCR antibody, Procr antibody
    Background
    Synonyms: EPCR
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