ITGA2 antibody
Quick Overview for ITGA2 antibody (ABIN2689304)
Target
See all ITGA2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Brand
- BD Pharmingen™
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Characteristics
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The Ha1/29 antibody reacts with intergrin α2 chain (CD49b or VLA-2 α chain), the 160- kDa transmembrane glycoprotein that non-covalently associates with the intergrin β1 subunit (CD29) to form the intergrin α2β1 complex known as VLA-2. VLA-2, a receptor for collagen and laminin, is expressed on activated lymphocytes, epithelial cells, and platelets. It has been reported that Ha1/29 antibody can block VLA-2 binding to collagen and laminin. Ha1/29 antibody also reacts with mouse CD49b. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.
BD Pharmingen™ Purified Hamster Anti-Rat CD49b - Purified - Clone Ha1/29 - Isotype Armenian Hamster IgG2, λ - Reactivity Rat, Ms - 0.5 mg -
Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Immunogen
- Cultured Rat Glomerular Epithelial
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Isotype
- IgG2 lambda
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store undiluted at 4°C.
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- ITGA2 (Integrin alpha 2 (ITGA2))
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Alternative Name
- CD49b
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Background
- Synonyms: Integrin α2 chain
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Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
Target
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