ITGA5 antibody

Catalog No. ABIN2689313

This Mouse Monoclonal antibody specifically detects ITGA5 in FACS. It exhibits reactivity toward Human and Pig and has been mentioned in 2+ publications.

Quick Overview for ITGA5 antibody (ABIN2689313)

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reactivity: Human, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA5 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: VC5

Product Details anti-ITGA5 Antibody

Brand: BD Pharmingen™

Characteristics: Reacts with the α5 integrin, a dimer of 135/25 kDa, that associates with β1 integrin (CD29) to form VLA-5, a well-established fibronectin receptor that is expressed on many cell types, including fibroblasts, endothelial cells, epithelial cells, platelets, peripheral T cells, the myeloid cell line U937, K562 and some melanoma cell lines. This clone does not inhibit α5β1/ligand binding. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD49e - Purified - Clone VC5 - Isotype Mouse IgG1, κ - Reactivity Hu, Pig - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-ITGA5 antibody (ABIN2689313)

Tran Van Nhieu, Isberg: "Bacterial internalization mediated by beta 1 chain integrins is determined by ligand affinity and receptor density." in: The EMBO journal, Vol. 12, Issue 5, pp. 1887-95, (1993) (PubMed).

Van Nhieu, Isberg: "The Yersinia pseudotuberculosis invasin protein and human fibronectin bind to mutually exclusive sites on the alpha 5 beta 1 integrin receptor." in: The Journal of biological chemistry, Vol. 266, Issue 36, pp. 24367-75, (1992) (PubMed).

Target Details for ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Alternative Name: CD49e

Background: Synonyms: Integrin α5 chain

Pathways: Integrin Complex