CD56 antibody

Catalog No. ABIN2689341

There are 6+ publications for this product available. The Mouse Monoclonal anti-CD56 antibody has been validated for FACS, IHC, Func and IAC. It is suitable to detect CD56 in samples from Rat.

Quick Overview for CD56 antibody (ABIN2689341)

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD56 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func), Immunoaffinity Chromatography (IAC)

Clone: MY31

Product Details anti-CD56 Antibody

Characteristics: Reacts with the neural cell adhesion molecule (N-CAM), CD56 antigen, 175-180 kD, a glycoprotein on natural killer (NK) lymphocytes, a subset of T lymphocytes and interleukin-2 (IL-2)-activated thymocytes, as well as neural and degenerating or diseased muscle tissue. Anti-N-CAM monoclonal antibody (clone MY31) immunoprecipitates NCAM from neuroblastoma, KG-1a.5, N-CAM-trasfected mouse L cells, and human adenocarcinoma cells.

BD Pharmingen™ Purified Mouse Anti-human CD56 - Purified - Clone MY31 - Isotype Mouse IgG1, κ - 0.2 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD56 antibody (ABIN2689341)

Doherty, Ashton, Moore, Walsh: "Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels." in: Cell, Vol. 67, Issue 1, pp. 21-33, (1991) (PubMed).

Jin, Hemperly, Lloyd: "Expression of neural cell adhesion molecule in normal and neoplastic human neuroendocrine tissues." in: The American journal of pathology, Vol. 138, Issue 4, pp. 961-9, (1991) (PubMed).

Lanier, Chang, Azuma, Ruitenberg, Hemperly, Phillips: "Molecular and functional analysis of human natural killer cell-associated neural cell adhesion molecule (N-CAM/CD56)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 12, pp. 4421-6, (1991) (PubMed).

Lanier, Testi, Bindl, Phillips: "Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule." in: The Journal of experimental medicine, Vol. 169, Issue 6, pp. 2233-8, (1989) (PubMed).

Schubert, Zimmermann, Cramer, Starzinski-Powitz: "Lymphocyte antigen Leu-19 as a molecular marker of regeneration in human skeletal muscle." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 307-11, (1989) (PubMed).

Lanier, Le, Civin, Loken, Phillips: "The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 136, Issue 12, pp. 4480-6, (1986) (PubMed).

Target Details for CD56

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Alternative Name: CD56

Background: Synonyms: N-CAM