Transferrin Receptor antibody (Biotin)

Catalog No. ABIN2689387

This anti-Transferrin Receptor antibody is a Mouse Monoclonal antibody detecting Transferrin Receptor in FACS. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Transferrin Receptor antibody (Biotin) (ABIN2689387)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: M

Product Details anti-Transferrin Receptor Antibody (Biotin)

Brand: BD Pharmingen™

Characteristics: Reacts with the 95 kDa, type II membrane glycoprotein, the transferrin receptor expressed on activated lymphocytes, monocytes, macrophages, most dividing cells and on brain endothelium. CD71 is not expressed on resting lymphocytes and is upregulated during response to antigens and/or mitogens. The transferrin receptor binds Fe(Apo)-transferrin and via endocytosis and delivers iron required by the growing cell for cellular metabolism. Profile of PHA-stimulated (3 days peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Biotin Mouse Anti-Human CD71 - Biotin - Clone M-A712 - Isotype Mouse IgG2a, κ - Reactivity Hu - 100 Tests

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Sample Volume: 20 μL

Restrictions: For Research Use only

Handling

Buffer: Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

References for anti-Transferrin Receptor antibody (Biotin) (ABIN2689387)

Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71

Background: Synonyms: Transferrin Receptor

Pathways: Transition Metal Ion Homeostasis