Follicular Dendritic Cells antibody

Catalog No. ABIN2689507

Cited in 2+ publications. The Rat Monoclonal anti-Follicular Dendritic Cells antibody (Clone FDC) (ABIN2689507) specifically detects Follicular Dendritic Cells in IHC (fro) and IHC (f). The antibody is reactive with Mouse samples.

Quick Overview for Follicular Dendritic Cells antibody (ABIN2689507)

Target: Follicular Dendritic Cells

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Follicular Dendritic Cells antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: FDC

Product Details anti-Follicular Dendritic Cells Antibody

Characteristics: Follicular Dendritic Cells (FDC) form a structural network within the lymphoid follicles and are involved in antigen presentation to B cells for generating an immune response and for the maintenance of immunological memory. FDCs are believed to provide signals to B cells to induce their proliferation. In LCMV mediated immunosuppression there is evidence of T-cell dependent destruction of macrophages and follicular dendritic cells. The FDC-M1 antibody recognizes follicular dendritic cells and their dendritic processes. Immunohistochemistry of follicular dendritic cells. Frozen sections of mouse spleen was reacted with the FDC-M1 antibody. Follicular dendritic cells can be identified by the intense brown labeling of their cell membranes. Magnification 20X.

BD Pharmingen™ Purified Rat Anti-Mouse Follicular Dendritic Cell - Purified - Clone FDC-M1 - Isotype Rat IgG2c, κ - Reactivity Ms - 1 mL

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2c kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-Follicular Dendritic Cells antibody (ABIN2689507)

Kosco, Pflugfelder, Gray: "Follicular dendritic cell-dependent adhesion and proliferation of B cells in vitro." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 8, pp. 2331-9, (1992) (PubMed).

Gray, Kosco, Stockinger: "Novel pathways of antigen presentation for the maintenance of memory." in: International immunology, Vol. 3, Issue 2, pp. 141-8, (1991) (PubMed).

Target Details for Follicular Dendritic Cells

Target: Follicular Dendritic Cells

Alternative Name: Follicular Dendritic Cell