Myeloperoxidase antibody

Catalog No. ABIN2689854

There is 1 publication for this product available. The Mouse Monoclonal anti-Myeloperoxidase antibody is suitable to detect Myeloperoxidase in samples from Human. It has been validated for IHC (fro), IHC (f), IHC (zinc) and ICS.

Quick Overview for Myeloperoxidase antibody (ABIN2689854)

Target: Myeloperoxidase (MPO)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Myeloperoxidase antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)), Intracellular Staining (ICS)

Clone: 1B10

Product Details anti-Myeloperoxidase Antibody

Characteristics: Reacts with myeloperoxidase (MPO), a hemoprotein of 140 kDa, composed of two heavy subunits of 52 kDa and two light chains of 15 kDa. MPO is stored in primary azurophilic granules of neutrophils and plays a major role in the bactericidal activity of neutrophils during phagocytosis. It catalyzes the generation of hypochlorous acid, a powerful oxidant. 1B10 antibody detects MPO in neutrophils, monocytes and HL-60 cells. This reagent is suitable for immunohistochemical staining of acetone-fixed, frozen tissue section, or formalin-fixed, paraffin-embedded tissue sections with TUF pretreatment, or zinc-fixed, paraffin-embedded tissue sections with no pretreatment.

BD Pharmingen™ Purified Mouse Anti-Human Myeloperoxidase - Purified - Clone 1B10 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-Myeloperoxidase antibody (ABIN2689854)

Audrain, Baranger, Moguilevski, Martin, Devys, Lockwood, Muller, Esnault: "Anti-native and recombinant myeloperoxidase monoclonals and human autoantibodies." in: Clinical and experimental immunology, Vol. 107, Issue 1, pp. 127-34, (1997) (PubMed).

Target Details for Myeloperoxidase

Target: Myeloperoxidase (MPO)

Alternative Name: Myeloperoxidase

Background: Synonyms: MPO

Pathways: Chromatin Binding