OPRD1 antibody (pSer363) (Biotin)

Catalog No. ABIN2690259

This anti-OPRD1 antibody is a Rabbit Polyclonal antibody detecting OPRD1 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human, Mouse and Rat.

Quick Overview for OPRD1 antibody (pSer363) (Biotin) (ABIN2690259)

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRD1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-OPRD1 Antibody (Biotin)

Binding Specificity: pSer363

Specificity: This phosphorylation site is homologous in the listed cross reactive species at the specified location.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OPRD1 around the phosphorylation site of TP(p-S)DG

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for OPRD1

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Alternative Name: OPRD1

Background:

Synonyms: OPRD, Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1

Background: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Gene ID: 4985

UniProt: P41143

Pathways: Protein targeting to Nucleus