OPRD1 antibody (pSer363) (Biotin)

Catalog No. ABIN2690259

The Biotin-conjugated Rabbit Polyclonal anti-OPRD1 antibody (ABIN2690259) specifically detects OPRD1 in WB, ELISA, IHC (p) and IHC (fro). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for OPRD1 antibody (pSer363) (Biotin) (ABIN2690259)

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRD1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-OPRD1 Antibody (Biotin)

Binding Specificity: pSer363

Specificity: This phosphorylation site is homologous in the listed cross reactive species at the specified location.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OPRD1 around the phosphorylation site of TP(p-S)DG

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for OPRD1

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Alternative Name: OPRD1

Background:

Synonyms: OPRD, Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1

Background: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Gene ID: 4985

UniProt: P41143

Pathways: Protein targeting to Nucleus