OTUD5 antibody (AA 501-571) (Biotin)

Catalog No. ABIN2690270

Product Details anti-OTUD5 Antibody (Biotin)

Target: OTUD5 (OTU Domain Containing 5 (OTUD5))

Binding Specificity: AA 501-571

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTUD5 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OTUD5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for OTUD5

Target: OTUD5 (OTU Domain Containing 5 (OTUD5))

Alternative Name: OTUD5 (OTUD5 Products)

Background:

Synonyms: DUBA, OTU domain-containing protein 5, Deubiquitinating enzyme A, OTUD5

Background: Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro).

Gene ID: 55593

UniProt: Q96G74